Information about the San Antonio Cancer Institute

The San Antonio Cancer Institute (SACI) is the product of the mutual cancer research programs of The University of Texas Health Science Center at San Antonio (UTHSCSA) and Cancer Therapy and Research Center (CTRC). The two institutions have successfully worked together since 1974 in researching cancer treatment and prevention. Through their collaboration, the San Antonio Cancer Institute have been able to create five research programs that include Cancer Prevention and Population Science, Cancer-Related Bone Diseases, Experimental Therapeutics, Genomic Integrity and Carcinogenesis, and Geriatric Oncology.

The UTHSCSA is renowned for its strong and varied science programs and clinical research competence as well as its exceptional academic institution. Combining these important features with CTRC’s outpatient cancer treatment abilities and facilities strengthens the purpose and effectiveness of the SACI.

Cancer is largely a disease in which human behavior, and environmental and societal factors play a significant causative role; an estimated 50-75% of cancer mortality is attributed to factors primarily related to human behaviors. Basic or applied research in the behavioral, social, and population sciences that focus on modification of such factors to reduce cancer risk, prevalence, incidence, and mortality is the premise of cancer control with the objective to improve public health.

The goals of the Cancer Prevention and Health Promotion Program are to: 
1. develop and expand research projects in cancer prevention and control that are transdisciplinary and integrate with the basic and clinical research programs of the San Antonio Cancer Institute (SACI); 
2. develop and enhance programs that address the cancer burden in South Texas among different ethnic populations.

Three major research foci have been identified in the CPPSP:

  • prostate cancer,
  • Hispanic populations, and
  • childhood cancers.

Potential overarching research themes to link the three major foci include:

  • Biomarkers
  • Chemoprevention
  • Childhood Cancer
  • Early Detection
  • Epidemiology/Surveillance
  • Ethnic Disparities
  • Genetic Polymorphisms
  • Obesity
  • Prostate Cancer
  • Risk Assessment

The prostate research projects encompass epidemiology, bio-markers, genetics, proteomics, and chemoprevention. Research in health disparities, especially in access and delivery of cancer care in Hispanic populations, and differential cancer burden between Hispanic and non-Hispanic populations is of particular interest. Pediatric cancer research currently is in the area of survivorship, compliance, and obesity, especially in acute lymphocytic leukemia (ALL) patients.